Recruitment from SPRINTR-Real study-ready population
Participants in SPRINTR-Real prospectively consent to being contacted with information about clinical trials for which they meet the inclusion and exclusion criteria.
SPRINTR-Trial
SPRINTR-Trial is the platform for biomarker-based clinical trials within SPRINTR. It builds on the study-ready population created in SPRINTR-Real, including clinical status and progress and biomarker profile, with the prospective consent to be matched to inclusion/exclusion criteria and selectively invited. Any interventional trial will need a separate ethical permit but may refer to SPRINTR-Real procedure for recruitment and data management.
Pre-screening for clinical trials
SPRINTR-Real includes molecular profiling data that may serve as a legally and ethically approved framework for pre-screening in any biomarker-driven clinical trial, reducing the administrative burden and costs associated with screening within a phase II-III trial (monitoring, AE registration).
Follow-up parameters from national registers
All participants in SPRINTR will be continuously followed through clinical data from registers, facilitating clinical trial procedures. Facilitating register-based Randomized Clinical Trials (R-RCT) and long-term follow-up after the clinical study stops.